Online courses directory (417)

This is a laboratory course supplemented by lectures that focus on selected analytical facilities that are commonly used to determine the mineralogy, elemental abundance and isotopic ratios of Sr and Pb in rocks, soils, sediments and water.

The course, which spans two thirds of a semester, provides students with a research-inspired laboratory experience that introduces standard biochemical techniques in the context of investigating a current and exciting research topic, acquired resistance to the cancer drug Gleevec. Techniques include protein expression, purification, and gel analysis, PCR, site-directed mutagenesis, kinase activity assays, and protein structure viewing.

This class is part of the new laboratory curriculum in the MIT Department of Chemistry. Undergraduate Research-Inspired Experimental Chemistry Alternatives (URIECA) introduces students to cutting edge research topics in a modular format.

Acknowledgments

Development of this course was funded through an HHMI Professors grant to Professor Catherine L. Drennan.

This course deals with a more advanced treatment of the biochemical mechanisms that underlie biological processes. Emphasis will be given to the experimental methods used to unravel how these processes fit into the cellular context as well as the coordinated regulation of these processes. Topics include macromolecular machines for energy and force transduction, regulation of biosynthetic and degradative pathways, and the structure and function of nucleic acids.

This course covers the principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. Mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Tissue and organ regeneration. Design of implants and prostheses based on control of biomaterials-tissue interactions. Comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to case studies. Criteria for restoration of physiological function for tissues and organs.

An advanced course covering anatomical, physiological, behavioral, and computational studies of the central nervous system relevant to speech and hearing. Students learn primarily by discussions of scientific papers on topics of current interest. Recent topics include cell types and neural circuits in the auditory brainstem, organization and processing in the auditory cortex, auditory reflexes and descending systems, functional imaging of the human auditory system, quantitative methods for relating neural responses to behavior, speech motor control, cortical representation of language, and auditory learning in songbirds.

This course focuses on computational and experimental analysis of biological systems across a hierarchy of scales, including genetic, molecular, cellular, and cell population levels. The two central themes of the course are modeling of complex dynamic systems and protein design and engineering. Topics include gene sequence analysis, molecular modeling, metabolic and gene regulation networks, signal transduction pathways and cell populations in tissues. Emphasis is placed on experimental methods, quantitative analysis, and computational modeling.

Do you have an interest in biology and quantitative tools? Do you know computational methods but do not realize how they apply to biological problems? Do you know biology but do not understand how scientists really analyze complicated data? 7.QBWx: Quantitative Biology Workshop is designed to give learners exposure to the application of quantitative tools to analyze biological data at an introductory level. For the last few years, the Biology Department of MIT has run this workshop-style course as part of a one-week outreach program for students from other universities. With 7.QBWx, we can give more learners from around the world the chance to discover quantitative biology. We hope that this series of workshops encourages learners to explore new interests and take more biology and computational courses.

We expect that learners from 7.00x Introduction to Biology – The Secret of Life or an equivalent course can complete this workshop-based course without a background in programming. The course content will introduce programming languages but will not teach any one language in a comprehensive manner. The content of each week varies. We want learners to have an introduction to multiple languages and tools to find a topic that they would want to explore more. Participants with programming experience will find some weeks easier than students with only biology experience, while those with a biology background should find the week on genetics easier. We recommend that learners try to complete each week to find what interests them the most.

Workshop Content Creators and Residential Leaders

Gregory Hale, Michael Goard, Ph.D., Ben Stinson, Kunle Demuren, Sara Gosline, Ph.D., Glenna Foight, Leyla Isik, Samir El-Boustani, Ph.D., Gerald Pho, and Rajeev Rikhye

Residential Outreach Workshop Organizer and Creator

Mandana Sassanfar, Ph.D.

This workshop includes activities on the following biological topics: population biology, biochemical equilibrium and kinetics, molecular modeling of enzymes, visual neuroscience, genetics, gene expression and development, and genomics. The tools and programming languages include MATLAB, PyMOL, StarGenetics, Python, and R. This course does not require learners to download MATLAB. All MATLAB activities run and are graded within the edX platform. We do recommend that participants download a few other free tools for the activities so that they learn how to use the same tools and programs that scientists use.

Build your earth science vocabulary and learn about cycles of matter and types of sedimentary rocks through the Education Portal course Earth Science 101: Earth Science. Our series of video lessons and accompanying self-assessment quizzes can help you boost your scientific knowledge ahead of the Excelsior Earth Science exam . This course was designed by experienced educators and examines both science basics, like experimental design and systems of measurement, and more advanced topics, such as analysis of rock deformation and theories of continental drift.

No region on Earth is immune from natural disasters. As we gain scientific understanding into the causes and nature of such phenomena, we become better able to mitigate the effects of disasters. Yet as the world's population continues to grow, an increasingly large number of people are at risk.

This science course examines different types of natural disasters and our ability, or inability, to control and predict such events. You will gain an appreciation of natural disasters beyond the newspaper headlines, and will better understand how the effects of disasters can be reduced.

There is an urgent need for people from all walks of life to better understand the scientific principles behind the occurrence of natural disasters:

• City planners need to know where, and where not, to site buildings.
• Politicians need to make scientifically informed decisions.
• Emergency management officials need to understand the nature of a potential disaster and ways to mitigate such an event.
• Journalists need to report scientifically accurate information.

Learner Testimonial:

“Professors Stix and Gyakum have created and presented an engaging course, and have helped in my quest for a better understanding of the world around me.” – Previous Student

The aim of this class is to introduce the exciting and often under appreciated discoveries in RNA biology by exploring the diversity of RNAs—encompassing classical molecules such as ribosomal RNAs (rRNAs), transfer RNAs (tRNAs) and messenger RNAs (mRNAs) as well as newer species, such as microRNAs (miRNAs), long-noncoding RNAs (lncRNAs), and circular RNAs (circRNAs). For each new class of RNA, we will evaluate the evidence for its existence as well as for its proposed function. Students will develop both a deep understanding of the field of RNA biology and the ability to critically assess new papers in this fast-paced field.

This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

Get a basic overview of microbiology before exploring advanced topics like bacterial cell morphology, nitrogen fixation and protozoan diseases through this online Education Portal course, Biology 103: Microbiology. Watch our video lessons on STDs, bacterial diseases and foodborne illnesses as you prepare to earn real college credit through the Microbiology Excelsior Exam . Though the subjects covered in these lessons are somewhat intense, our experienced, knowledgeable instructors have kept the videos brief, engaging and easy to follow. You also can benefit from the multiple-choice quizzes and written transcripts that complement each video.

Biomimetics is based on the belief that nature, at least at times, is a good engineer. Biomimesis is the scientific method of learning new principles and processes based on systematic study, observation and experimentation with live animals and organisms. This Freshman Advising Seminar on the topic is a way for freshmen to explore some of MIT's richness and learn more about what they may want to study in later years.

The goal of this course is to teach both the fundamentals of nuclear cell biology as well as the methodological and experimental approaches upon which they are based. Lectures and class discussions will cover the background and fundamental findings in a particular area of nuclear cell biology. The assigned readings will provide concrete examples of the experimental approaches and logic used to establish these findings. Some examples of topics include genome and systems biology, transcription, and gene expression.

Mechanical forces play a decisive role during development of tissues and organs, during remodeling following injury as well as in normal function. A stress field influences cell function primarily through deformation of the extracellular matrix to which cells are attached. Deformed cells express different biosynthetic activity relative to undeformed cells. The unit cell process paradigm combined with topics in connective tissue mechanics form the basis for discussions of several topics from cell biology, physiology, and medicine.

This is an undergraduate introductory laboratory subject in ocean chemistry and measurement. There are three main elements to the course: oceanic chemical sampling and analysis, instrumentation development for the ocean environment, and the larger field of ocean science.

This course is offered through The MIT/WHOI Joint Program. The MIT/WHOI Joint Program is one of the premier marine science graduate programs in the world. It draws on the complementary strengths and approaches of two great institutions: the Massachusetts Institute of Technology (MIT) and the Woods Hole Oceanographic Institution (WHOI).

This course is an intensive introduction to the techniques of experimental chemistry and gives first year students an opportunity to learn and master the basic chemistry lab techniques for carrying out experiments. Students who successfully complete the course and obtain a "Competent Chemist" (CC) or "Expert Experimentalist" (EE) rating are likely to secure opportunities for research work in a chemistry lab at MIT.

Acknowledgements

The laboratory manual and materials for this course were prepared by Dr. Katherine J. Franz and Dr. Kevin M. Shea with the assistance of Professors Rick L. Danheiser and Timothy M. Swager. Materials have been revised by Dr. J. Haseltine, Dr. Kevin M. Shea, Dr. Sarah A. Tabacco, Dr. Kimberly L. Berkowski, Anne M. (Gorham) Rachupka, and Dr. John J. Dolhun.