Online courses directory (182)
This course focuses on the interaction of chemical engineering, biochemistry, and microbiology. Mathematical representations of microbial systems are featured among lecture topics. Kinetics of growth, death, and metabolism are also covered. Continuous fermentation, agitation, mass transfer, and scale-up in fermentation systems, and enzyme technology round out the subject material.
This course illustrates how knowledge and principles of biology, biochemistry, and engineering are integrated to create new products for societal benefit. It uses a case study format to examine recently developed products of pharmaceutical and biotechnology industries: how a product evolves from initial idea, through patents, testing, evaluation, production, and marketing. Emphasizes scientific and engineering principles; the responsibility scientists, engineers, and business executives have for the consequences of their technology; and instruction and practice in written and oral communication.
The topic focus of this class will vary from year to year. This version looks at inflammation underlying many diseases, specifically its role in cancer, diabetes, and cardiovascular disease.
This course covers sensing and measurement for quantitative molecular/cell/tissue analysis, in terms of genetic, biochemical, and biophysical properties. Methods include light and fluorescence microscopies; electro-mechanical probes such as atomic force microscopy, laser and magnetic traps, and MEMS devices; and the application of statistics, probability and noise analysis to experimental data. Enrollment preference is given to juniors and seniors.
In this course problems from biological engineering are used to develop structured computer programming skills and explore the theory and practice of complex systems design and construction.
The official course Web site can be viewed at: BE.180 Biological Engineering Programming.
This course provides intensive coverage of the theory and practice of electromechanical instrument design with application to biomedical devices. Students will work with MGH doctors to develop new medical products from concept to prototype development and testing. Lectures will present techniques for designing electronic circuits as part of complete sensor systems. Topics covered include: basic electronics circuits, principles of accuracy, op amp circuits, analog signal conditioning, power supplies, microprocessors, wireless communications, sensors, and sensor interface circuits. Labs will cover practical printed circuit board (PCB) design including component selection, PCB layout, assembly, and planning and budgeting for large projects. Problem sets and labs in the first six weeks are in support of the project. Major team-based design, build, and test project in the last six weeks. Student teams will be composed of both electrical engineering and mechanical engineering students.
This course consists of a series of seminars focused on the development of professional skills. Each semester focuses on a different topic, resulting in a repeating cycle that covers medical ethics, responsible conduct of research, written and oral technical communication, and translational issues. Material and activities include guest lectures, case studies, interactive small group discussions, and role-playing simulations.
TV programs such as "Law and Order" show how forensic experts are called upon to give testimony that often determines the outcome of court cases. Engineers are one class of expert who can help display evidence in a new light to solve cases. In this seminar you will be part of the problem-solving process, working through both previously solved and unsolved cases. Each week we will investigate cases, from the facts that make up each side to the potential evidence we can use as engineers to expose culprits. The cases range from disintegrating airplane engines to gas main explosions to Mafia murders. This seminar will be full of discussions about the cases and creative approaches to reaching the solutions. The approach is hands-on so you will have a chance to participate in the process, not simply study it. Some background reading and oral presentation are required.
This course applies the concepts of reaction rate, stoichiometry and equilibrium to the analysis of chemical and biological reacting systems, derivation of rate expressions from reaction mechanisms and equilibrium or steady state assumptions, design of chemical and biochemical reactors via synthesis of chemical kinetics, transport phenomena, and mass and energy balances. Topics covered include: chemical/biochemical pathways; enzymatic, pathway, and cell growth kinetics; batch, plug flow and well-stirred reactors for chemical reactions and cultivations of microorganisms and mammalian cells; heterogeneous and enzymatic catalysis; heat and mass transport in reactors, including diffusion to and within catalyst particles and cells or immobilized enzymes.
This course aims to connect the principles, concepts, and laws/postulates of classical and statistical thermodynamics to applications that require quantitative knowledge of thermodynamic properties from a macroscopic to a molecular level. It covers their basic postulates of classical thermodynamics and their application to transient open and closed systems, criteria of stability and equilibria, as well as constitutive property models of pure materials and mixtures emphasizing molecular-level effects using the formalism of statistical mechanics. Phase and chemical equilibria of multicomponent systems are covered. Applications are emphasized through extensive problem work relating to practical cases.
This core class in the Environmental M.Eng. program is for all students interested in the behavior of chemicals in the environment. The emphasis is on man-made chemicals; their movement through water, air, and soil; and their eventual fate. Physical transport, as well as chemical and biological sources and sinks, are discussed. Linkages to health effects, sources and control, and policy aspects are discussed and debated.
6.002 is designed to serve as a first course in an undergraduate electrical engineering (EE), or electrical engineering and computer science (EECS) curriculum. At MIT, 6.002 is in the core of department subjects required for all undergraduates in EECS.
The course introduces the fundamentals of the lumped circuit abstraction. Topics covered include: resistive elements and networks; independent and dependent sources; switches and MOS transistors; digital abstraction; amplifiers; energy storage elements; dynamics of first- and second-order networks; design in the time and frequency domains; and analog and digital circuits and applications. Design and lab exercises are also significant components of the course. 6.002 is worth 4 Engineering Design Points. The 6.002 content was created collaboratively by Profs. Anant Agarwal and Jeffrey H. Lang.
The course uses the required textbook Foundations of Analog and Digital Electronic Circuits. Agarwal, Anant, and Jeffrey H. Lang. San Mateo, CA: Morgan Kaufmann Publishers, Elsevier, July 2005. ISBN: 9781558607354.
This course introduces the concepts, techniques, and devices used to measure engineering properties of materials. There is an emphasis on measurement of load-deformation characteristics and failure modes of both natural and fabricated materials. Weekly experiments include data collection, data analysis, and interpretation and presentation of results.
2.26 is a 6-unit Honors-level subject serving as the Mechanical Engineering department's sole course in compressible fluid dynamics. The prerequisites for this course are undergraduate courses in thermodynamics, fluid dynamics, and heat transfer.
The goal of this course is to lay out the fundamental concepts and results for the compressible flow of gases. Topics to be covered include: appropriate conservation laws; propagation of disturbances; isentropic flows; normal shock wave relations, oblique shock waves, weak and strong shocks, and shock wave structure; compressible flows in ducts with area changes, friction, or heat addition; heat transfer to high speed flows; unsteady compressible flows, Riemann invariants, and piston and shock tube problems; steady 2D supersonic flow, Prandtl-Meyer function; and self-similar compressible flows. The emphasis will be on physical understanding of the phenomena and basic analytical techniques.
This course covers the analytical, graphical, and numerical methods supporting the analysis and design of integrated biological systems. Topics include modularity and abstraction in biological systems, mathematical encoding of detailed physical problems, numerical methods for solving the dynamics of continuous and discrete chemical systems, statistics and probability in dynamic systems, applied local and global optimization, simple feedback and control analysis, statistics and probability in pattern recognition.
An official course Web site and Wiki is maintained on OpenWetWare: 20.181 Computation for Biological Engineers.
Topics in surface modeling: b-splines, non-uniform rational b-splines, physically based deformable surfaces, sweeps and generalized cylinders, offsets, blending and filleting surfaces. Non-linear solvers and intersection problems. Solid modeling: constructive solid geometry, boundary representation, non-manifold and mixed-dimension boundary representation models, octrees. Robustness of geometric computations. Interval methods. Finite and boundary element discretization methods for continuum mechanics problems. Scientific visualization. Variational geometry. Tolerances. Inspection methods. Feature representation and recognition. Shape interrogation for design, analysis, and manufacturing. Involves analytical and programming assignments.
This course was originally offered in Course 13 (Department of Ocean Engineering) as 13.472J. In 2005, ocean engineering subjects became part of Course 2 (Department of Mechanical Engineering), and this course was renumbered 2.158J.
16.225 is a graduate level course on Computational Mechanics of Materials. The primary focus of this course is on the teaching of state-of-the-art numerical methods for the analysis of the nonlinear continuum response of materials. The range of material behavior considered in this course includes: linear and finite deformation elasticity, inelasticity and dynamics. Numerical formulation and algorithms include: variational formulation and variational constitutive updates, finite element discretization, error estimation, constrained problems, time integration algorithms and convergence analysis. There is a strong emphasis on the (parallel) computer implementation of algorithms in programming assignments. The application to real engineering applications and problems in engineering science is stressed throughout the course.
This course serves as an introduction to computational techniques arising in aerospace engineering. Applications are drawn from aerospace structures, aerodynamics, dynamics and control, and aerospace systems. Techniques include: numerical integration of systems of ordinary differential equations; finite-difference, finite-volume, and finite-element discretization of partial differential equations; numerical linear algebra; eigenvalue problems; and optimization with constraints.
This course examines wave equations for fluid and visco-elastic media, wave-theory formulations of acoustic source radiation and seismo-acoustic propagation in stratified ocean waveguides, and Wavenumber Integration and Normal Mode methods for propagation in plane-stratified media. Also covered are Seismo-Acoustic modeling of seabeds and ice covers, seismic interface and surface waves in a stratified seabed, Parabolic Equation and Coupled Mode approaches to propagation in range-dependent ocean waveguides, numerical modeling of target scattering and reverberation clutter in ocean waveguides, and ocean ambient noise modeling. Students develop propagation models using all the numerical approaches relevant to state-of-the-art acoustic research.
This course was originally offered in Course 13 (Department of Ocean Engineering) as 13.853. In 2005, ocean engineering subjects became part of Course 2 (Department of Mechanical Engineering), and this course was renumbered 2.068.
This course provides a review of linear algebra, including applications to networks, structures, and estimation, Lagrange multipliers. Also covered are: differential equations of equilibrium; Laplace's equation and potential flow; boundary-value problems; minimum principles and calculus of variations; Fourier series; discrete Fourier transform; convolution; and applications.
Note: This course was previously called "Mathematical Methods for Engineers I."
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