# Online courses directory (16)

This introductory course in biology starts at the microscopic level, with molecules and cells. Before we get into the specifics of cell structure and behavior, however, let’s take a cursory glance at the field of biology more generally. Though biology as we know it today is a relatively new field, we have been studying living things since the beginning of recorded history. The invention of the microscope was the turning point in the history of biology; it paved the way for scientists to discover bacteria and other tiny organisms and ultimately led to the modern cell theory of biology. You will notice that, unlike the core program courses you took in chemistry and physics, introductory biology does not have many mathematical “laws” and “rules” and does not require much math. Instead, you will learn a great number of new terms and concepts that will help you describe life at the smallest level. Over the course of this semester, you will recognize the ways in which the tiniest of molecules are involved…

This course is designed to introduce you to the study of Calculus. You will learn concrete applications of how calculus is used and, more importantly, why it works. Calculus is not a new discipline; it has been around since the days of Archimedes. However, Isaac Newton and Gottfried Leibniz, two 17th-century European mathematicians concurrently working on the same intellectual discovery hundreds of miles apart, were responsible for developing the field as we know it today. This brings us to our first question, what is today's Calculus? In its simplest terms, calculus is the study of functions, rates of change, and continuity. While you may have cultivated a basic understanding of functions in previous math courses, in this course you will come to a more advanced understanding of their complexity, learning to take a closer look at their behaviors and nuances. In this course, we will address three major topics: limits, derivatives, and integrals, as well as study their respective foundations and a…

The advent of computers transformed science. Large, complicated datasets that once took researchers years to manually analyze could suddenly be analyzed within a week using computer software. Nowadays, scientists can use computers to produce several hypotheses as to how a particular phenomenon works, create computer models using the parameters of each hypothesis, input data, and see which hypothetical model produces an output that most closely mirrors reality. Computational biology refers to the use of computers to automate data analysis or model hypotheses in the field of biology. With computational biology, researchers apply mathematics to biological phenomena, use computer programming and algorithms to artificially create or model the phenomena, and draw from statistics in order to interpret the findings. In this course, you will learn the basic principles and procedures of computational biology. You will also learn various ways in which you can apply computational biology to molecular and cell…

This is an introductory course in biochemistry, designed for both biology and chemical engineering majors. A consistent theme in this course is the development of a quantitative understanding of the interactions of biological molecules from a structural, thermodynamic, and molecular dynamic point of view. A molecular simulation environment provides the opportunity for you to explore the effect of molecular interactions on the biochemical properties of systems. This course assumes that students have taken introductory chemistry, including basic thermodynamics, as well as introductory organic chemistry. An introductory biology course is not a prerequisite for the course, but students would benefit from some prior exposure to biology, even at the high school level. Required mathematical skills include simple algebra and differential calculus.

This subject deals primarily with kinetic and equilibrium mathematical models of biomolecular interactions, as well as the application of these quantitative analyses to biological problems across a wide range of levels of organization, from individual molecular interactions to populations of cells.

Life as an emergent property of networks of chemical reactions involving proteins and nucleic acids. Mathematical theories of metabolism, gene regulation, signal transduction, chemotaxis, excitability, motility, mitosis, development, and immunity. Applications to directed molecular evolution, DNA computing, and metabolic and genetic engineering.

This course covers cells and tissues of the immune system, lymphocyte development, the structure and function of antigen receptors, the cell biology of antigen processing and presentation, including molecular structure and assembly of MHC molecules, the biology of cytokines, leukocyte-endothelial interactions, and the pathogenesis of immunologically mediated diseases. The course is structured as a series of lectures and tutorials in which clinical cases are discussed with faculty tutors.

#### Lecturers

Frederick W. Alt

Marcus Altfeld

Paul Anderson

Jon C. Aster

Hugh Auchincloss

Steven P. Balk

Samuel M. Behar

Richard S. Blumberg

Francisco Bonilla

Bobby Cherayil

Benjamin Davis

David Hafler

Nir Harcohen

Bruce Horwitz

David M. Lee

Andrew Lichtman

Diane Mathis

Richard Mitchell

Hidde Ploegh

Emmett Schmidt

Arlene Sharpe

Megan Sykes

Shannon Turley

Dale T. Umetsu

Ulrich von Andrian

Bruce Walker

Kai Wucherpfennig

Ramnik Xavier

Sarah Henrickson