Courses tagged with "Diencephalon" (58)

This course is designed to look at the topics covered in advanced high school chemistry courses, correlating to the standard topics as established by the American Chemical Society. Engaging instruction and supplemental video demonstrations are designed to help prepare students for college level chemistry.

This seminar will be a scientific exploration of the food we eat and enjoy. Each week we shall have a scientific edible experiment that will explore a specific food topic. This will be a hands-on seminar with mandatory attendance of at least 85%. Topics include, but are not limited to, what makes a good experiment, cheese making, joys of tofu, food biochemistry, the science of spice, what is taste?

This course is the second in a series of two courses in kitchen chemistry. The prerequisite to Advanced Kitchen Chemistry is ES.287 Kitchen Chemistry, which is also on OCW.

This course deals with the application of structure and theory to the study of organic reaction mechanisms: Stereochemical features including conformation and stereoelectronic effects; reaction dynamics, isotope effects and molecular orbital theory applied to pericyclic and photochemical reactions; and special reactive intermediates including carbenes, carbanions, and free radicals.

If chemistry is the science of stuff, then analytical chemistry answers the question: what is it? And how much of it do you have? This course teaches how to do this with instrumental analysis!

The course, which spans two thirds of a semester, provides students with a research-inspired laboratory experience that introduces standard biochemical techniques in the context of investigating a current and exciting research topic, acquired resistance to the cancer drug Gleevec. Techniques include protein expression, purification, and gel analysis, PCR, site-directed mutagenesis, kinase activity assays, and protein structure viewing.

This class is part of the new laboratory curriculum in the MIT Department of Chemistry. Undergraduate Research-Inspired Experimental Chemistry Alternatives (URIECA) introduces students to cutting edge research topics in a modular format.

Acknowledgments

Development of this course was funded through an HHMI Professors grant to Professor Catherine L. Drennan.

This course deals with a more advanced treatment of the biochemical mechanisms that underlie biological processes. Emphasis will be given to the experimental methods used to unravel how these processes fit into the cellular context as well as the coordinated regulation of these processes. Topics include macromolecular machines for energy and force transduction, regulation of biosynthetic and degradative pathways, and the structure and function of nucleic acids.

Physics 101 is the first course in the Introduction to Physics sequence. In general, the quest of physics is to develop descriptions of the natural world that correspond  closely to actual observations.  Given this definition, the story behind everything in the universe is  one of physics.  In practice,  the field of physics is more often limited to the discovery and refinement of the basic laws that underlie the behavior of matter and energy.  While biology is founded upon physics, in practice, the study of biology generally assumes that the present understanding of physical laws is accurate.  Chemistry is more closely dependent on physics and   assumes that physical laws provide accurate predictions.  Engineering, for the most part, is applied physics. In this course, we will study physics from the ground up, learning the basic principles of physical laws, their application to the behavior of objects, and the use of the scientific method in driving advances in this knowledge.  This first course o…

The physics of the Universe appears to be dominated by the effects of four fundamental forces: gravity, electromagnetism, and weak and strong nuclear forces.  These control how matter, energy, space, and time interact to produce our physical world.  All other forces, such as the force you exert in standing up, are ultimately derived from these fundamental forces. We have direct daily experience with two of these forces: gravity and electromagnetism.  Consider, for example, the everyday sight of a person sitting on a chair.  The force holding the person on the chair is gravitational, while that gravitational force is balanced by material forces that “push up” to keep the individual in place, and these forces are the direct result of electromagnetic forces on the nanoscale.  On a larger stage, gravity holds the celestial bodies in their orbits, while we see the Universe by the electromagnetic radiation (light, for example) with which it is filled.  The electromagnetic force also makes possible the a…

This course is designed to introduce you to the study of Calculus.  You will learn concrete applications of how calculus is used and, more importantly, why it works.  Calculus is not a new discipline; it has been around since the days of Archimedes.  However, Isaac Newton and Gottfried Leibniz, two 17th-century European mathematicians concurrently working on the same intellectual discovery hundreds of miles apart, were responsible for developing the field as we know it today.  This brings us to our first question, what is today's Calculus?  In its simplest terms, calculus is the study of functions, rates of change, and continuity.  While you may have cultivated a basic understanding of functions in previous math courses, in this course you will come to a more advanced understanding of their complexity, learning to take a closer look at their behaviors and nuances. In this course, we will address three major topics: limits, derivatives, and integrals, as well as study their respective foundations and a…

This course is the second installment of Single-Variable Calculus.  In Part I (MA101) [1], we studied limits, derivatives, and basic integrals as a means to understand the behavior of functions.  In this course (Part II), we will extend our differentiation and integration abilities and apply the techniques we have learned. Additional integration techniques, in particular, are a major part of the course.  In Part I, we learned how to integrate by various formulas and by reversing the chain rule through the technique of substitution.  In Part II, we will learn some clever uses of substitution, how to reverse the product rule for differentiation through a technique called integration by parts, and how to rewrite trigonometric and rational integrands that look impossible into simpler forms.  Series, while a major topic in their own right, also serve to extend our integration reach: they culminate in an application that lets you integrate almost any function you’d like. Integration allows us to calculat…

This chemistry survey is designed to introduce students to the world of chemistry.  The principles of chemistry were first identified, studied, and applied by ancient Egyptians in order to extract metal from ores, make alcoholic beverages, glaze pottery, turn fat into soap, and much more.  What began as a quest to build better weapons or create potions capable of ensuring everlasting life has since become the foundation of modern science.  Take a look around you: chemistry makes up almost everything you touch, see, and feel, from the shampoo you used this morning to the plastic container that holds your lunch.  In this course, we will study chemistry from the ground up, learning the basics of the atom and its behavior.  We will use this knowledge to understand the chemical properties of matter and the changes and reactions that take place in all types of matter.

In this second semester course, we will cover a wide-ranging field of topics, learning everything from the equation that made Einstein famous to why you can’t replace a dead car battery with a household battery. In General Chemistry I (CHEM101 [1]), we studied the basic tools you need to explore different fields in chemistry, such as stoichiometry and thermodynamics.  This second-semester course will cover several of the tools needed to study chemistry at a more advanced level.  We will identify the factors that affect the speed of a reaction, learn how an atom bomb works on a chemical level, and discover how chemistry powers a light bulb.  Topics in advanced organic and inorganic chemistry courses will build upon what you learn in this class.  We will end with discussion of organic chemistry, a topic that is as important to biology as it is to chemistry. [1] http:///courses/chem101/…

Organic chemistry is a branch of chemistry that focuses on a single element: carbon!  Carbon bonds strongly with other carbon atoms and with other elements, forming numerous chain and ring structures.  As a result, there are millions of distinct carbon compounds known and classified.  The vast majority of the molecules that contain carbon are considered organic molecules, with few debatable exceptions such as carbon nanotubes, diamonds, carbonate ions, and carbon dioxide.  Carbon is central to the existence of life as it is an essential component of nucleic acids (DNA and RNA), sugars, lipids, and proteins.  A well-rounded student of science must take courses in organic chemistry to understand its application to various topics, such as the study of polymers (plastics and other materials), hydrocarbons, pharmaceuticals, molecular biology, biochemistry, and other life sciences. In the first semester of organic chemistry, you will learn the basic concepts needed to understand the three-dimensional structu…

This course is a continuation of CHEM103 [1]: Organic Chemistry I.  As you progress through the units below, you will continue to learn the different chemical reactions characteristic of each family of organic compounds.  We will focus on the four most important classes of reactions: electrophilic substitution at aromatic rings, nucleophilic addition at carbonyl compounds, hydrolysis of carboxylic acids, and carbon-carbon bond formation using enolates.  The enolate portion of this course will cover the reactivity of functional groups. We will also look at synthetic strategies for making simple, small organic molecules, using the knowledge of organic chemistry accumulated thus far.  At the end of this course, you will possess the tools you need to plan the synthesis of fairly complicated molecules, like those used in pharmaceutics.  From the perspective of a synthetic organic chemist, the two most challenging aspects of synthesizing drug molecules are the incorporation of  "molecular rings" (rings of 5…

This course will teach you the fundamentals of thermodynamics. Thermodynamics is the study of energy and its transformations. Energy is a physical property that can be converted from one form to another in order to perform work. For example, a stone rolling down a hill is converting gravitational potential energy into the kinetic energy of motion. Thermodynamics can be applied to systems we use every daysuch as, for example, heat pumps and refrigerators, internal combustion engines, batteries, and both electrical and mechanical power generators. An awareness of thermodynamics will help you examine other concepts involving chemical processes more quickly and will enable you to understand why many physical phenomena (such as automobile engines or chemical explosives) work the way they do. The knowledge you will gain in this course also will help you determine how much work an object can put out and predict how to optimize an object’s operation. In this course, you will learn about the laws of thermodynamics…

Physical Chemistry II is quite different from Physical Chemistry I.  In this second semester of the Physical Chemistry course, you will study the principles and laws of quantum mechanics as well as the interaction between matter and electromagnetic waves.  During the late 19th century and early 20th century, scientists opened new frontiers in the understanding of matter at the molecular, atomic, and sub-atomic scale.  These studies resulted in the development of quantum physics, which nowadays is still considered one of the greatest achievements of human mind.  While present day quantum physics “zooms in” to look at subatomic particles, quantum chemistry “zooms out” to look at large molecular systems in order to theoretically understand their physical and chemical properties.  Quantum chemistry has created certain “tools” (or computational methods) based on the laws of quantum mechanics that make it theoretically possible to understand how electrons and atomic nuclei interact with each other…

Inorganic chemistry is a division of chemistry that studies metals, their compounds, and their reactivity.  Metal atoms can be bound to other metal atoms in alloys or metal clusters, to nonmetal elements in crystalline rocks, or to small organic molecules, such as a cyclopentadienyl anion in ferrocene.  These metal atoms can also be part of large biological molecules, as in the case of iron in hemoglobin (oxygen-carrier protein in the blood). In this course, you should not think of metals as you encounter them in your daily life (i.e., when you pick up a steel knife, a can of soda, or a gold necklace).  Instead, you should think of a metal as the central atom or ion in a molecule surrounded by other ions or small molecules called ligands.  Depending on what these ligands are, the metal-containing compound can acquire very different physical and chemical properties.  For example, when magnesium (in its ionic state) is bound to carbonate ions, it forms solid crystalline rocks, as in the dolomite rocks (c…

Analytical chemistry is the branch of chemistry dealing with measurement, both qualitative and quantitative.  This discipline is also concerned with the chemical composition of samples.  In the field, analytical chemistry is applied when detecting the presence and determining the quantities of chemical compounds, such as lead in water samples or arsenic in tissue samples.  It also encompasses many different spectrochemical techniques, all of which are used under various experimental conditions.  This branch of chemistry teaches the general theories behind the use of each instrument as well analysis of experimental data. This course begins with a review of general chemistry and an introduction to analytical terminology.  You will learn terms relevant to the process of measuring chemical compounds, such as sensitivity and detection limit.  The course continues with a unit on common spectrochemical methods, followed by an extension of these methods in a unit on atomic spectroscopy.  These methods allow…

Biochemistry is the study of the chemical processes and compounds, such as cellular makeup, that bring about life in organisms.  It is a combination of multiple science fields; you can think of it as general and cell biology coupled with organic and general chemistry.  Although living organisms are very complex, from a molecular view, the material that constitutes “life” can be broken down into remarkably simple molecules, much like the breakdown of our English language to the English alphabet.  Although there exists thousands upon thousands of molecules, they all breakdown into four core components: nucleic acids, amino acids, lipids, and carbohydrates.  As we can make hundreds of thousands of words from just 26 letters, we can make thousands of different biomolecules from those 4 components.  For example, the human genome, containing the necessary information to create a human being, is really just one very long strand of 4 different nucleotides. This course is structured around that approach, so…