This course is designed to provide an understanding of how the human brain works in health and disease, and is intended for both the Brain and Cognitive Sciences major and the non-Brain and Cognitive Sciences major. Knowledge of how the human brain works is important for all citizens, and the lessons to be learned have enormous implications for public policy makers and educators.
The course will cover the regional anatomy of the brain and provide an introduction to the cellular function of neurons, synapses and neurotransmitters. Commonly used drugs that alter brain function can be understood through a knowledge of neurotransmitters. Along similar lines, common diseases that illustrate normal brain function will be discussed. Experimental animal studies that reveal how the brain works will be reviewed.
Throughout the seminar we will discuss clinical cases from Dr. Byrne's experience that illustrate brain function; in addition, articles from the scientific literature will be discussed in each class.
Introduction to the linguistic study of language pathology, concentrating on experimental approaches and theoretical explanations. Discussion of Specific Language Impairment, autism, Down syndrome, Williams syndrome, normal aging, Parkinson's disease, Alzheimer's disease, hemispherectomy and aphasia. Focuses on the comparison of linguistic abilities among these syndromes, while drawing clear comparisons with first and second language acquisition. Topics include the lexicon, morphology, syntax, semantics and pragmatics. Relates the lost linguistic abilities in these syndromes to properties of the brain.
This course will begin with brief overview of what important current research topics are in oceanography (physical, geological, and biological) and how acoustics can be used as a tool to address them. Three typical examples are climate, bottom geology, and marine mammal behavior. Will then address the acoustic inverse problem, reviewing inverse methods (linear and nonlinear) and the combination of acoustical methods with other measurements as an integrated system. Last part of course will concentrate on specific case studies, taken from current research journals. This course is taught on campus at MIT and with simultaneous video at Woods Hole Oceanographic Institution.
The course includes survey and special topics designed for graduate students in the brain and cognitive sciences. It emphasizes ethological studies of natural behavior patterns and their analysis in laboratory work, with contributions from field biology (mammology, primatology), sociobiology, and comparative psychology. It stresses mammalian behavior but also includes major contributions from studies of other vertebrates and of invertebrates. It covers some applications of animal-behavior knowledge to neuropsychology and behavioral pharmacology.
5.33 focuses on advanced experimentation, with particular emphasis on chemical synthesis and the fundamentals of quantum chemistry, illustrated through molecular spectroscopy. The written and oral presentation of experimental results is also emphasized in the course.
The materials for 5.33 reflect the work of many faculty members associated with this course over the years.
The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or implementation of any of the material presented.
This course is designed to look at the topics covered in advanced high school chemistry courses, correlating to the standard topics as established by the American Chemical Society. Engaging instruction and supplemental video demonstrations are designed to help prepare students for college level chemistry.
This seminar will be a scientific exploration of the food we eat and enjoy. Each week we shall have a scientific edible experiment that will explore a specific food topic. This will be a hands-on seminar with mandatory attendance of at least 85%. Topics include, but are not limited to, what makes a good experiment, cheese making, joys of tofu, food biochemistry, the science of spice, what is taste?
This course is the second in a series of two courses in kitchen chemistry. The prerequisite to Advanced Kitchen Chemistry is ES.287 Kitchen Chemistry, which is also on OCW.
This course deals with the application of structure and theory to the study of organic reaction mechanisms: Stereochemical features including conformation and stereoelectronic effects; reaction dynamics, isotope effects and molecular orbital theory applied to pericyclic and photochemical reactions; and special reactive intermediates including carbenes, carbanions, and free radicals.
This course studies the relations of affect to cognition and behavior, feeling to thinking and acting, and values to beliefs and practices. These connections will be considered at the psychological level of organization and in terms of their neurobiological and sociocultural counterparts.
This course is an investigation of affective priming and creation of rigorously counterbalanced, fully computerized testing paradigm. Includes background readings, study design, counterbalancing, study execution, data analysis, presentation of poster, and final paper.
This course will discuss HIV/AIDS in the US and around the world including its history, science, and culture as well as developments in behavioral and biomedical prevention, experimental AIDS vaccines, and clinical care issues. The course will also include a discussion of the populations that are particularly vulnerable to HIV/AIDS and a look at future challenges facing people infected and affected by the AIDS pandemic.
This is a discussion-based interactive seminar on the two major issues that affect Sub-Saharan Africa: HIV/AIDS and Poverty. AIDS and Poverty, seemingly different concepts, are more inter-related to each other in Africa than in any other continent. As MIT students, we feel it is important to engage ourselves in a dynamic discussion on the relation between the two - how to fight one and how to solve the other.
The aim of this class is to introduce the exciting and often under appreciated discoveries in RNA biology by exploring the diversity of RNAs—encompassing classical molecules such as ribosomal RNAs (rRNAs), transfer RNAs (tRNAs) and messenger RNAs (mRNAs) as well as newer species, such as microRNAs (miRNAs), long-noncoding RNAs (lncRNAs), and circular RNAs (circRNAs). For each new class of RNA, we will evaluate the evidence for its existence as well as for its proposed function. Students will develop both a deep understanding of the field of RNA biology and the ability to critically assess new papers in this fast-paced field.
This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
This class analyzes complex biological processes from the molecular, cellular, extracellular, and organ levels of hierarchy. Emphasis is placed on the basic biochemical and biophysical principles that govern these processes. Examples of processes to be studied include chemotaxis, the fixation of nitrogen into organic biological molecules, growth factor and hormone mediated signaling cascades, and signaling cascades leading to cell death in response to DNA damage. In each case, the availability of a resource, or the presence of a stimulus, results in some biochemical pathways being turned on while others are turned off. The course examines the dynamic aspects of these processes and details how biochemical mechanistic themes impinge on molecular/cellular/tissue/organ-level functions. Chemical and quantitative views of the interplay of multiple pathways as biological networks are emphasized. Student work culminates in the preparation of a unique grant application in an area of biological networks.
This course focuses on computational and experimental analysis of biological systems across a hierarchy of scales, including genetic, molecular, cellular, and cell population levels. The two central themes of the course are modeling of complex dynamic systems and protein design and engineering. Topics include gene sequence analysis, molecular modeling, metabolic and gene regulation networks, signal transduction pathways and cell populations in tissues. Emphasis is placed on experimental methods, quantitative analysis, and computational modeling.
This is a laboratory course supplemented by lectures that focus on selected analytical facilities that are commonly used to determine the mineralogy, elemental abundance and isotopic ratios of Sr and Pb in rocks, soils, sediments and water.
The introductory topics will cover various approaches to the study of animals and their behavior. Key concepts in studies of animal behavior, emphasizing ethology, are covered in class and in the assigned readings from Scott (2005), supplemented by selections from other books, especially from classics in the field as well as selected videos. Next, key concepts in sociobiology are covered using readings from Alcock (2001), supplemented by selections from additional books and some video presentations.