Online courses directory (417)

Understanding how the brain works is one of the fundamental challenges in science today. This course will introduce you to basic computational techniques for analyzing, modeling, and understanding the behavior of cells and circuits in the brain. You do not need to have any prior background in neuroscience to take this course.

The Lungs and Pulmonary System. Red blood cells. Circulatory System and the Heart. Hemoglobin. Anatomy of a Neuron. Sodium Potassium Pump. Correction to Sodium and Potassium Pump Video. Electrotonic and Action Potentials. Saltatory Conduction in Neurons. Neuronal Synapses (Chemical). Myosin and Actin. Tropomyosin and troponin and their role in regulating muscle contraction. Role of the Sarcoplasmic Reticulum in Muscle Cells. Anatomy of a muscle cell. The Kidney and Nephron. Secondary Active Transport in the Nephron. The Lungs and Pulmonary System. Red blood cells. Circulatory System and the Heart. Hemoglobin. Anatomy of a Neuron. Sodium Potassium Pump. Correction to Sodium and Potassium Pump Video. Electrotonic and Action Potentials. Saltatory Conduction in Neurons. Neuronal Synapses (Chemical). Myosin and Actin. Tropomyosin and troponin and their role in regulating muscle contraction. Role of the Sarcoplasmic Reticulum in Muscle Cells. Anatomy of a muscle cell. The Kidney and Nephron. Secondary Active Transport in the Nephron.

Nerves, the heart, and the brain are electrical. How do these things work? This course presents fundamental principles, described quantitatively.

This course teaches scientists to become more effective writers, using practical examples and exercises. Topics include: principles of good writing, tricks for writing faster and with less anxiety, the format of a scientific manuscript, and issues in publication and peer review.

An introduction to dynamical modeling techniques used in contemporary Systems Biology research.

This introduction to fundamental chemical concepts of atomic and molecular structure will emphasize the development of these concepts from experimental observations and scientific reasoning.

Step into the world of Tissue Engineering, a rapidly expanding field of applied biology aiming to create artificial organs for transplantation, basic research, or drug development.

Introduction to Heredity. Punnett Square Fun. Hardy-Weinberg Principle. Sex-Linked Traits. Genetics 101 Part 1: What are genes?. Genetics 101 Part 2: What are SNPs?. Genetics 101 Part 3: Where do your genes come from?. Genetics 101 Part 4: What are Phenotypes?. Introduction to Heredity. Punnett Square Fun. Hardy-Weinberg Principle. Sex-Linked Traits. Genetics 101 Part 1: What are genes?. Genetics 101 Part 2: What are SNPs?. Genetics 101 Part 3: Where do your genes come from?. Genetics 101 Part 4: What are Phenotypes?.

This introductory course provides an overview of the principles of nutritional science. Subject matter includes description and functions of nutrients, digestion and absorption, effects of nutrient deficiencies and toxicities, requirements, food sources, nutrient interactions, dietary guidelines, and the role of nutrition in health and disease.

Groups of the Periodic Table. Valence Electrons. Periodic Table Trends: Ionization Energy. Other Periodic Table Trends. Ionic, Covalent, and Metallic Bonds. Groups of the Periodic Table. Valence Electrons. Periodic Table Trends: Ionization Energy. Other Periodic Table Trends. Ionic, Covalent, and Metallic Bonds.

To acquire an understanding of the fundamental concepts of genomics and biotechnology, and their implications for human biology, evolution, medicine, social policy and individual life path choices in the 21st century.

chirality, stereoisomers, assigning absolute configuration using the R,S system, optical activity, diastereomers, meso compounds, fischer projections. Introduction to Chirality. Chiral Examples 1. Chiral Examples 2. Cahn-Ingold-Prelog System for Naming Enantiomers. R,S (Cahn-Ingold-Prelog) Naming System Example 2. chirality centers and stereoisomers. R,S system for determining absolute configuration. R,S system for cyclic compounds. optical activity I: theory. optical activity II: calculations. Stereoisomers, Enantiomers, Diastereomers, Constitutional Isomers and Meso Compounds. diastereomers. meso compounds. fischer projections. Introduction to Chirality. Chiral Examples 1. Chiral Examples 2. Cahn-Ingold-Prelog System for Naming Enantiomers. R,S (Cahn-Ingold-Prelog) Naming System Example 2. chirality centers and stereoisomers. R,S system for determining absolute configuration. R,S system for cyclic compounds. optical activity I: theory. optical activity II: calculations. Stereoisomers, Enantiomers, Diastereomers, Constitutional Isomers and Meso Compounds. diastereomers. meso compounds. fischer projections.

conjugation, conjugated dienes, addition reactions of conjugated dienes, diels-alder reaction, MO theory, color. addition reaction of conjugated dienes I: mechanism. addition reaction of conjugated dienes II: example. addition reaction of conjugated dienes III: control. diels-alder I: mechanism. diels-alder II: endo vs exo. diels-alder III: stereochemistry of dienophile. diels-alder IV: stereochemistry of diene. diels-alder V: regiochemistry. diels-alder VI: more regiochemistry. diels-alder VII: intramolecular. intro to molecular orbital (MO) theory. MO theory for butadiene. MO theory for Diels-Alder. intro to color theory. conjugation and color. color in organic molecules. addition reaction of conjugated dienes I: mechanism. addition reaction of conjugated dienes II: example. addition reaction of conjugated dienes III: control. diels-alder I: mechanism. diels-alder II: endo vs exo. diels-alder III: stereochemistry of dienophile. diels-alder IV: stereochemistry of diene. diels-alder V: regiochemistry. diels-alder VI: more regiochemistry. diels-alder VII: intramolecular. intro to molecular orbital (MO) theory. MO theory for butadiene. MO theory for Diels-Alder. intro to color theory. conjugation and color. color in organic molecules.

nomenclature and reactions of amines. Amine Naming Introduction. Amine Naming 2. Amine as Nucleophile in Sn2 Reaction. Amine in Sn2 part 2. Sn1 Amine Reaction. Amine Naming Introduction. Amine Naming 2. Amine as Nucleophile in Sn2 Reaction. Amine in Sn2 part 2. Sn1 Amine Reaction.

SN1, SN2, E1, E2, nucleophiles, nucleophilicity, basicity. Naming Alkyl Halides. Sn2 Reactions. Sn1 Reactions. Steric hindrance. Sn2 Stereochemistry. Solvent Effects on Sn1 and Sn2 Reactions. Nucleophilicity (Nucleophile Strength). Nucleophilicity vs. Basicity. E2 Reactions. E1 Reactions. Zaitsev's Rule. Comparing E2 E1 Sn2 Sn1 Reactions. E2 E1 Sn2 Sn1 Reactions Example 2. E2 E1 Sn2 Sn1 Reactions Example 3. nucleophile/electrophile and The Schwartz Rules. alkyl halide nomenclature. SN1 reaction: mechanism. SN1 reaction: stereochemistry. SN2 mechanism and stereochemistry. SN1 vs SN2: solvent effects. SN1 vs SN2: summary. E1 Elimination: mechanism. E1 Elimination: regioselectivity and stereoselectivity. carbocations and rearrangements. E1 Elimination: carbocation rearrangements. E2 Elimination: mechanism. E2 Elimination: regioselectivity. E2 Elimination: stereoselectivity. E2 Elimination: stereospecificity. E2 Elimination: substituted cyclohexanes. nucleophilicity and basicity. SN1 SN2 E1 E2 reactions: primary and tertiary alkyl halides. SN1 SN2 E1 E2 reactions: secondary alkyl halides. Naming Alkyl Halides. Sn2 Reactions. Sn1 Reactions. Steric hindrance. Sn2 Stereochemistry. Solvent Effects on Sn1 and Sn2 Reactions. Nucleophilicity (Nucleophile Strength). Nucleophilicity vs. Basicity. E2 Reactions. E1 Reactions. Zaitsev's Rule. Comparing E2 E1 Sn2 Sn1 Reactions. E2 E1 Sn2 Sn1 Reactions Example 2. E2 E1 Sn2 Sn1 Reactions Example 3. nucleophile/electrophile and The Schwartz Rules. alkyl halide nomenclature. SN1 reaction: mechanism. SN1 reaction: stereochemistry. SN2 mechanism and stereochemistry. SN1 vs SN2: solvent effects. SN1 vs SN2: summary. E1 Elimination: mechanism. E1 Elimination: regioselectivity and stereoselectivity. carbocations and rearrangements. E1 Elimination: carbocation rearrangements. E2 Elimination: mechanism. E2 Elimination: regioselectivity. E2 Elimination: stereoselectivity. E2 Elimination: stereospecificity. E2 Elimination: substituted cyclohexanes. nucleophilicity and basicity. SN1 SN2 E1 E2 reactions: primary and tertiary alkyl halides. SN1 SN2 E1 E2 reactions: secondary alkyl halides.

A review of hybrid orbitals, dot structures, electronegativity, and polarity. sp3 Hybridized Orbitals and Sigma Bonds. Pi bonds and sp2 Hybridized Orbitals. dot structures I: single bonds. dot structures II: multiple bonds. sp3 hybrid orbitals. tetrahedral bond angle proof. sp2 hybrid orbitals. sp hybrid orbitals. more hybridization. electronegativity. electronegativity and intermolecular forces. sp3 Hybridized Orbitals and Sigma Bonds. Pi bonds and sp2 Hybridized Orbitals. dot structures I: single bonds. dot structures II: multiple bonds. sp3 hybrid orbitals. tetrahedral bond angle proof. sp2 hybrid orbitals. sp hybrid orbitals. more hybridization. electronegativity. electronegativity and intermolecular forces.

aromatic compounds, naming derivatives of benzene, electrophilic aromatic substitution reactions. Naming Benzene Derivatives Introduction. naming benzene derivatives. Aromatic Compounds and Huckel's Rule. Aromatic Stability I. aromatic stability II. aromatic stability III. aromatic stability IV. aromatic stability V. Aromatic Heterocycles I. Aromatic Heterocycles II. Resonance. Electrophilic Aromatic Substitution. Bromination of Benzene. Friedel Crafts Acylation. Friedel Crafts Acylation Addendum. Electrophilic Aromatic Substitution Mechanism. Halogenation. Nitration. Sulfonation. Friedel-Crafts Alkylation. Friedel-Crafts Acylation. Ortho-Para Directors I. Ortho-Para Directors II. Ortho-Para Directors III. Meta Directors I. Meta Directors II. Multiple Substituents. Birch Reduction I. Birch Reduction II. Reactions at the Benzylic Position. Synthesis of Substituted Benzene Rings I. Synthesis of Substituted Benzene Rings II. Nucleophilic Aromatic Substitution I. Nucleophilic Aromatic Substitution II. Naming Benzene Derivatives Introduction. naming benzene derivatives. Aromatic Compounds and Huckel's Rule. Aromatic Stability I. aromatic stability II. aromatic stability III. aromatic stability IV. aromatic stability V. Aromatic Heterocycles I. Aromatic Heterocycles II. Resonance. Electrophilic Aromatic Substitution. Bromination of Benzene. Friedel Crafts Acylation. Friedel Crafts Acylation Addendum. Electrophilic Aromatic Substitution Mechanism. Halogenation. Nitration. Sulfonation. Friedel-Crafts Alkylation. Friedel-Crafts Acylation. Ortho-Para Directors I. Ortho-Para Directors II. Ortho-Para Directors III. Meta Directors I. Meta Directors II. Multiple Substituents. Birch Reduction I. Birch Reduction II. Reactions at the Benzylic Position. Synthesis of Substituted Benzene Rings I. Synthesis of Substituted Benzene Rings II. Nucleophilic Aromatic Substitution I. Nucleophilic Aromatic Substitution II.

alcohols, ethers, epoxides, thiols, sulfides. Alcohols. Alcohol Properties. alcohol nomenclature. physical properties of alcohols and preparation of alkoxides. preparation of alcohols using NaBH4. preparation of alcohols using LiAlH4. synthesis of alcohols using grignard reagents I. synthesis of alcohols using grignard reagents II. oxidation of alcohols I: mechanism and oxidation states. oxidation of alcohols II: examples. biological redox reactions. formation of nitrate esters. preparation of alkyl halides from alcohols. Ether Naming and Introduction. Ether nomenclature. Properties of ethers and crown ethers. williamson ether synthesis. acidic cleavage of ethers. Cyclic ethers and epoxide naming. nomenclature and preparation of epoxides. preparation of epoxides: stereochemistry. Ring-opening Sn2 reaction of expoxides. Sn1 and Sn2 epoxide opening discussion. ring-opening reactions of epoxides: strong nucleophiles. ring opening reactions of epoxides: acid-catalyzed. preparation of sulfides. Alcohols. Alcohol Properties. alcohol nomenclature. physical properties of alcohols and preparation of alkoxides. preparation of alcohols using NaBH4. preparation of alcohols using LiAlH4. synthesis of alcohols using grignard reagents I. synthesis of alcohols using grignard reagents II. oxidation of alcohols I: mechanism and oxidation states. oxidation of alcohols II: examples. biological redox reactions. formation of nitrate esters. preparation of alkyl halides from alcohols. Ether Naming and Introduction. Ether nomenclature. Properties of ethers and crown ethers. williamson ether synthesis. acidic cleavage of ethers. Cyclic ethers and epoxide naming. nomenclature and preparation of epoxides. preparation of epoxides: stereochemistry. Ring-opening Sn2 reaction of expoxides. Sn1 and Sn2 epoxide opening discussion. ring-opening reactions of epoxides: strong nucleophiles. ring opening reactions of epoxides: acid-catalyzed. preparation of sulfides.

naming carboxylic acids, formation of carboxylic acid derivatives. Carboxlic Acid Introduction. Carboxylic Acid Naming. Fisher Esterification. Acid Chloride Formation. Amides, Anhydrides, Esters and Acyl Chlorides. Relative Stability of Amides Esters Anhydrides and Acyl Chlorides. Amide Formation from Acyl Chloride. Carboxlic Acid Introduction. Carboxylic Acid Naming. Fisher Esterification. Acid Chloride Formation. Amides, Anhydrides, Esters and Acyl Chlorides. Relative Stability of Amides Esters Anhydrides and Acyl Chlorides. Amide Formation from Acyl Chloride.

naming alkenes and alkynes, reactions of alkenes and alkynes, synthesis. Naming Alkenes Examples. Cis-Trans and E-Z Naming Scheme for Alkenes. Entgegen-Zusammen Naming Scheme for Alkenes Examples. Introduction to Reaction Mechanisms. Markovnikov's Rule and Carbocations. Addition of Water (Acid-Catalyzed) Mechanism. Polymerization of Alkenes with Acid. Alkene intro and stability. Alkene nomenclature. cis/trans and the E/Z system. hydrogenation. hydrohalogenation. hydration. halogenation. halohydrin formation. hydroboration-oxidation. epoxide formation and anti dihydroxylation. syn dihydroxylation. Ozonolysis. alkyne nomenclature. alkyne acidity and alkylation. preparation of alkynes. reduction of alkynes. hydrohalogenation of alkynes. hydration of alkynes. hydroboration-oxidation of alkynes. halogenation and ozonolysis of alkynes. synthesis using alkynes. Naming Alkenes Examples. Cis-Trans and E-Z Naming Scheme for Alkenes. Entgegen-Zusammen Naming Scheme for Alkenes Examples. Introduction to Reaction Mechanisms. Markovnikov's Rule and Carbocations. Addition of Water (Acid-Catalyzed) Mechanism. Polymerization of Alkenes with Acid. Alkene intro and stability. Alkene nomenclature. cis/trans and the E/Z system. hydrogenation. hydrohalogenation. hydration. halogenation. halohydrin formation. hydroboration-oxidation. epoxide formation and anti dihydroxylation. syn dihydroxylation. Ozonolysis. alkyne nomenclature. alkyne acidity and alkylation. preparation of alkynes. reduction of alkynes. hydrohalogenation of alkynes. hydration of alkynes. hydroboration-oxidation of alkynes. halogenation and ozonolysis of alkynes. synthesis using alkynes.