Courses tagged with "Graduate" (48)
This course will begin with brief overview of what important current research topics are in oceanography (physical, geological, and biological) and how acoustics can be used as a tool to address them. Three typical examples are climate, bottom geology, and marine mammal behavior. Will then address the acoustic inverse problem, reviewing inverse methods (linear and nonlinear) and the combination of acoustical methods with other measurements as an integrated system. Last part of course will concentrate on specific case studies, taken from current research journals. This course is taught on campus at MIT and with simultaneous video at Woods Hole Oceanographic Institution.
The course includes survey and special topics designed for graduate students in the brain and cognitive sciences. It emphasizes ethological studies of natural behavior patterns and their analysis in laboratory work, with contributions from field biology (mammology, primatology), sociobiology, and comparative psychology. It stresses mammalian behavior but also includes major contributions from studies of other vertebrates and of invertebrates. It covers some applications of animal-behavior knowledge to neuropsychology and behavioral pharmacology.
This class analyzes complex biological processes from the molecular, cellular, extracellular, and organ levels of hierarchy. Emphasis is placed on the basic biochemical and biophysical principles that govern these processes. Examples of processes to be studied include chemotaxis, the fixation of nitrogen into organic biological molecules, growth factor and hormone mediated signaling cascades, and signaling cascades leading to cell death in response to DNA damage. In each case, the availability of a resource, or the presence of a stimulus, results in some biochemical pathways being turned on while others are turned off. The course examines the dynamic aspects of these processes and details how biochemical mechanistic themes impinge on molecular/cellular/tissue/organ-level functions. Chemical and quantitative views of the interplay of multiple pathways as biological networks are emphasized. Student work culminates in the preparation of a unique grant application in an area of biological networks.
This course details the quantitative treatment of chemical processes in aquatic systems such as lakes, oceans, rivers, estuaries, groundwaters, and wastewaters. It includes a brief review of chemical thermodynamics that is followed by discussion of acid-base, precipitation-dissolution, coordination, and reduction-oxidation reactions. Emphasis is on equilibrium calculations as a tool for understanding the variables that govern the chemical composition of aquatic systems and the fate of inorganic pollutants.
This course is offered through The MIT/WHOI Joint Program. The MIT/WHOI Joint Program is one of the premier marine science graduate programs in the world. It draws on the complementary strengths and approaches of two great institutions: the Massachusetts Institute of Technology (MIT) and the Woods Hole Oceanographic Institution (WHOI).
This course provides a detailed overview of the chemical transformations that control the abundances of key trace species in the Earth's atmosphere. Emphasizes the effects of human activity on air quality and climate. Topics include photochemistry, kinetics, and thermodynamics important to the chemistry of the atmosphere; stratospheric ozone depletion; oxidation chemistry of the troposphere; photochemical smog; aerosol chemistry; and sources and sinks of greenhouse gases and other climate forcers.
This course covers the principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. Mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Tissue and organ regeneration. Design of implants and prostheses based on control of biomaterials-tissue interactions. Comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to case studies. Criteria for restoration of physiological function for tissues and organs.
This subject deals primarily with kinetic and equilibrium mathematical models of biomolecular interactions, as well as the application of these quantitative analyses to biological problems across a wide range of levels of organization, from individual molecular interactions to populations of cells.
An advanced course covering anatomical, physiological, behavioral, and computational studies of the central nervous system relevant to speech and hearing. Students learn primarily by discussions of scientific papers on topics of current interest. Recent topics include cell types and neural circuits in the auditory brainstem, organization and processing in the auditory cortex, auditory reflexes and descending systems, functional imaging of the human auditory system, quantitative methods for relating neural responses to behavior, speech motor control, cortical representation of language, and auditory learning in songbirds.
This course explores the major areas of cellular and molecular neurobiology, including excitable cells and membranes, ion channels and receptors, synaptic transmission, cell-type determination, axon guidance, neuronal cell biology, neurotrophin signaling and cell survival, synapse formation and neural plasticity. Material includes lectures and exams, and involves presentation and discussion of primary literature. It focuses on major concepts and recent advances in experimental neuroscience.
The goal of this course is to teach both the fundamentals of nuclear cell biology as well as the methodological and experimental approaches upon which they are based. Lectures and class discussions will cover the background and fundamental findings in a particular area of nuclear cell biology. The assigned readings will provide concrete examples of the experimental approaches and logic used to establish these findings. Some examples of topics include genome and systems biology, transcription, and gene expression.
Mechanical forces play a decisive role during development of tissues and organs, during remodeling following injury as well as in normal function. A stress field influences cell function primarily through deformation of the extracellular matrix to which cells are attached. Deformed cells express different biosynthetic activity relative to undeformed cells. The unit cell process paradigm combined with topics in connective tissue mechanics form the basis for discussions of several topics from cell biology, physiology, and medicine.
Life as an emergent property of networks of chemical reactions involving proteins and nucleic acids. Mathematical theories of metabolism, gene regulation, signal transduction, chemotaxis, excitability, motility, mitosis, development, and immunity. Applications to directed molecular evolution, DNA computing, and metabolic and genetic engineering.
This course covers cells and tissues of the immune system, lymphocyte development, the structure and function of antigen receptors, the cell biology of antigen processing and presentation, including molecular structure and assembly of MHC molecules, the biology of cytokines, leukocyte-endothelial interactions, and the pathogenesis of immunologically mediated diseases. The course is structured as a series of lectures and tutorials in which clinical cases are discussed with faculty tutors.
Frederick W. Alt
Jon C. Aster
Steven P. Balk
Samuel M. Behar
Richard S. Blumberg
David M. Lee
Dale T. Umetsu
Ulrich von Andrian
Other OCW Versions